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Phenotypes Associated with This Genotype
Genotype
MGI:3759306
Allelic
Composition
Nr3c1tm2Gsc/Nr3c1tm2Gsc
Tg(Camk2a-cre/ERT2)2Gsc/0
Genetic
Background
involves: 129P2/OlaHsd * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nr3c1tm2Gsc mutation (1 available); any Nr3c1 mutation (35 available)
Tg(Camk2a-cre/ERT2)2Gsc mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• when treated with tamoxifen the level of serum corticosterone is increased to 39+/-8 ng/ml when one copies of the transgene is present, 100+/-20 ng/ml when two copies of the transgene are present and 108+/-19 ng/ml when four copies of the transgene are present compared to 13+/-5 ng/ml in wild-type


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/17/2024
MGI 6.24
The Jackson Laboratory