Phenotypes Associated with This Genotype

Genotype
MGI:3764681

• Allelic Composition: Tg(APOC1)1Lmh/?
• Genetic Background: C57BL/6-Tg(APOC1)1Lmh

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

increased circulating cholesterol level ( J:65146 )

• serum cholesterol levels are slightly elevated in males on a normal chow diet

• serum cholesterol levels are elevated in males on a sucrose-rich diet; females show less pronounced increases

• serum cholesterol levels are increased more than in wild-type when on high fat diet (0.25% cholesterol, 15% cocoa butter)

increased circulating VLDL cholesterol level ( J:65146 )

increased circulating triglyceride level ( J:65146 )

• serum triglyceride levels are increased 3-fold in males on a normal chow diet

• serum triglyceride levels are elevated in males on a sucrose-rich diet; females show less pronounced increases

increased circulating VLDL triglyceride level ( J:65146 )