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Phenotypes Associated with This Genotype
Genotype
MGI:3776856
Allelic
Composition		 Atoh1tm2Hzo/Atoh1+
Tcf4tm1Zhu/Tcf4+
Genetic
Background		 involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atoh1tm2Hzo mutation (1 available); any Atoh1 mutation (37 available)
Tcf4tm1Zhu mutation (0 available); any Tcf4 mutation (58 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
neonatal lethality ( J:125313 )
• mice die within the first 24 hours of birth but no embryonic lethality is observed as previously noted

nervous system
abnormal brain development ( J:125313 )
• the pontine nuclei is disrupted

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory