Phenotypes for Apoa1 Apoa2 MGI:3783891 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Apoa1^tm1Bres/Apoa1^tm1Bres Apoa2^tm1Bres/Apoa2^tm1Bres
Genetic Background	involves: 129S4/SvJae * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apoa1^tm1Bres mutation (0 available); any Apoa1 mutation (16 available)
Apoa2^tm1Bres mutation (5 available); any Apoa2 mutation (20 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

decreased circulating HDL cholesterol level ( J:40819 )

• mice exhibit a further 50% or more reduction in HDL-C levels compared to in Apoa1^tm1Bres homozygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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