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Phenotypes Associated with This Genotype
Genotype
MGI:3795555
Allelic
Composition		 Sfrp1tm1Aksh/Sfrp1tm1Aksh
Sfrp2tm1Aksh/Sfrp2+
Sfrp5tm1Aksh/Sfrp5tm1Aksh
Vangl2Lp/Vangl2+
Genetic
Background		 involves: 129 * A * C57BL/6 * LPT/LeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sfrp1tm1Aksh mutation (1 available); any Sfrp1 mutation (19 available)
Sfrp2tm1Aksh mutation (1 available); any Sfrp2 mutation (30 available)
Sfrp5tm1Aksh mutation (0 available); any Sfrp5 mutation (27 available)
Vangl2Lp mutation (2 available); any Vangl2 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
spina bifida ( J:135313 )
• 62% of mice exhibit spina bifida

embryo
spina bifida ( J:135313 )
• 62% of mice exhibit spina bifida

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory