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Phenotypes Associated with This Genotype
Genotype
MGI:3796175
Allelic
Composition		 Stat3tm1Aki/Stat3tm1Aki
Tg(Tek-cre)12Flv/0
Genetic
Background		 involves: 129P2/OlaHsd * C3H * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stat3tm1Aki mutation (6 available); any Stat3 mutation (72 available)
Tg(Tek-cre)12Flv mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal interleukin level ( J:123351 )
• activated TH cells from mutants produce no Il-21, Il-17, Il-17F or Il-22

immune system
abnormal interleukin level ( J:123351 )
• activated TH cells from mutants produce no Il-21, Il-17, Il-17F or Il-22

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory