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Phenotypes Associated with This Genotype
Genotype
MGI:3797602
Allelic
Composition
Lsamptm1Afpi/Lsamptm1Afpi
Genetic
Background
B6.129-Lsamptm1Afpi
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lsamptm1Afpi mutation (0 available); any Lsamp mutation (26 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• mutants are hyperresponsive to novel environments
• mutants display hyperactivity in a novel open arena and although both sexes habituate to the same activity levels as wild-type, they do so at different rates
• in the elevated plus maze, mutants exhibit increases in open arm time, increases in open arm entries and increases in unprotected head-dips
• in the y-maze, mutants exhibit hyperactivity and a decrease in levels of spontaneous alternation during the period when their novelty-induced hyperactivity is at its peak


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/17/2024
MGI 6.24
The Jackson Laboratory