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Phenotypes Associated with This Genotype
Genotype
MGI:3798173
Allelic
Composition		 Vdrtm1Mbd/Vdr+
Genetic
Background		 involves: 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Vdrtm1Mbd mutation (1 available); any Vdr mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
cardiovascular system phenotype ( J:120353 )
N
• plasma levels of angiotensin II or aldosterone are not different from wild-type
• ECG analysis does not reveal any significant differences from wild-type at 3, 6, or 9 months
increased heart weight ( J:120353 )
• heart weight to body weight ratio is increased 14% relative to wild-type

growth/size/body
increased heart weight ( J:120353 )
• heart weight to body weight ratio is increased 14% relative to wild-type

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/17/2024
MGI 6.24 		The Jackson Laboratory