Phenotypes Associated with This Genotype

Genotype
MGI:3799102

• Allelic Composition: Gnai2^tm1Lbi/Gnai2^tm1Lbi; Tg(WTbeta2)4Wjk/0
• Genetic Background: B6.Cg-Gnai2^tm1Lbi Tg(WTbeta2)4Wjk

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, complete penetrance ( J:125581 )

• all pups die between 1 and 4 days after birth

embryonic lethality, incomplete penetrance ( J:125581 )

• less then half of the expected Mendelian distribution for pups of this genotype are present at birth

growth/size/body

decreased birth body size ( J:125581 )

• pups are smaller than littermate controls at birth

behavior/neurological

weakness ( J:125581 )

• pups are weaker than littermate controls at birth

cardiovascular system

dilated heart ( J:125581 )

• dilated hearts are found at necropsy of mice that die shortly after birth