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Phenotypes Associated with This Genotype
Genotype
MGI:3799366
Allelic
Composition
jb/jb
Genetic
Background
involves: C3HeB/FeJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
jb mutation (1 available); any jb mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial
• breeding females, but not males or virgin females, are prone to incisor overgrowth and breakage, possibly due to poor mineralization

growth/size/body
• breeding females, but not males or virgin females, are prone to incisor overgrowth and breakage, possibly due to poor mineralization
• in some breeding females, likely associated with bad incisors

reproductive system

behavior/neurological
• convulsions are seen occasionally when the mutants are disturbed, such as when transfered between cages, and after these convulsions the mice are described as unusually nervous

nervous system
• convulsions are seen occasionally when the mutants are disturbed, such as when transfered between cages, and after these convulsions the mice are described as unusually nervous

integument
• Background Sensitivity: at 14 to 15 days of age hair loss begins and progresses from rump forward, stopping by 20 to 21 days of age at a line on the head between the ears. After this the hair regrows from the head forward to the rump and males have an almost nomral coat and females have a slightly sparce coat, which becomes more sparse with age (J:39707)
• Background Sensitivity: in females after regrowth of the coat

skeleton
• breeding females, but not males or virgin females, are prone to incisor overgrowth and breakage, possibly due to poor mineralization


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/17/2024
MGI 6.24
The Jackson Laboratory