immune system
• CD11b+ Langerhans cells and alveolar macrophage are depleted following intratracheally administration of diphtheria toxin
• mesenteric lymph nodes are partially depleted following intratracheally administration of diphtheria toxin
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• CD11b+ Langerhans cells and alveolar macrophage are depleted following intratracheally administration of diphtheria toxin
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• following administration of diphtheria toxin and CD3 stimulation, IFN-gamma production by CD4 and CD8 T cells from the mesenteric lymph nodes is decreased compared to in similarly treated wild-type mice
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• following intratracheally administration of diphtheria toxin, mice exhibit increased severity of influenza infection, increased weight loss and delayed clearance compared to infected wild-type mice
• the number of virus-specific cytotoxic T lymphoctes is reduced in mice treated with diphtheria toxin and infected with influenza compared to similarly treated wild-type mcie
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respiratory system
• CD11b+ Langerhans cells and alveolar macrophage are depleted following intratracheally administration of diphtheria toxin
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hematopoietic system
• CD11b+ Langerhans cells and alveolar macrophage are depleted following intratracheally administration of diphtheria toxin
• mesenteric lymph nodes are partially depleted following intratracheally administration of diphtheria toxin
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• CD11b+ Langerhans cells and alveolar macrophage are depleted following intratracheally administration of diphtheria toxin
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