Phenotypes Associated with This Genotype

Genotype
MGI:3801188

• Allelic Composition: Map3k10^tm1Lex/Map3k10^tm1Lex; Map3k9^tm1Lex/Map3k9^tm1Lex
• Genetic Background: either: 129S-Map3k10^tm1Lex Map3k9^tm1Lex or B6.129S-Map3k10^tm1Lex Map3k9^tm1Lex

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

mortality/aging ( J:137358 )

N • despite a lack of compensation from Map3k11, mice have normal life spans

reproductive system

reproductive system phenotype ( J:137358 )

N • despite a lack of compensation from Map3k11, mice breed normally

N • despite expression in the testis, testicular development is normal

embryo

embryo phenotype ( J:137358 )

N • despite a lack of compensation from Map3k11, mice develop normally

muscle

muscle phenotype ( J:137358 )

N • despite expression in the femoral muscle, skeletal muscle organization is normal

nervous system

nervous system phenotype ( J:137358 )

N • despite expression in the brain, nervous system development and cell death in the superior cervical ganglia are normal

renal/urinary system

renal/urinary system phenotype ( J:137358 )

N • despite endogenous expression in the kidneys, renal morphology and function are normal

digestive/alimentary system

digestive/alimentary phenotype ( J:137358 )

N • despite expression in the spleen and stomach, their morphology and function are normal