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Phenotypes Associated with This Genotype
Genotype
MGI:3802943
Allelic
Composition		 Sucnr1tm1Lex/Sucnr1tm1Lex
Genetic
Background		 involves: 129S/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sucnr1tm1Lex mutation (1 available); any Sucnr1 mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased circulating renin level ( J:137706 )
• high-glucose stimulation of rennin release in granules from the juxtaglomerular apparatus is decreased in non-diabetic and STZ-diabetic mice compared to in similar wild-type mice

renal/urinary system
abnormal kidney physiology ( J:137706 )
• high-glucose stimulation of rennin release in granules from the juxtaglomerular apparatus is decreased in non-diabetic and STZ-diabetic mice compared to in similar wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory