About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3803024
Allelic
Composition		 Tcf12tm1Zhu/Tcf12tm1Zhu
Genetic
Background		 involves: 129S7/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tcf12tm1Zhu mutation (0 available); any Tcf12 mutation (75 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
thymus hypoplasia ( J:136143 )
• thymi cultured for 7 days exhibit reduced total cell numbers compared to wild-type thymi
increased double-negative T cell number ( J:136143 )
• most pronounced in DN3 cells

hematopoietic system
thymus hypoplasia ( J:136143 )
• thymi cultured for 7 days exhibit reduced total cell numbers compared to wild-type thymi
increased double-negative T cell number ( J:136143 )
• most pronounced in DN3 cells

endocrine/exocrine glands
thymus hypoplasia ( J:136143 )
• thymi cultured for 7 days exhibit reduced total cell numbers compared to wild-type thymi

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory