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Phenotypes Associated with This Genotype
Genotype
MGI:3804085
Allelic
Composition
Cited2tm1Bha/Cited2tm2Bha
Edil3Tg(Sox2-cre)1Amc/Edil3+
Genetic
Background
involves: 129 * C57BL/6 * CBA * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cited2tm1Bha mutation (3 available); any Cited2 mutation (23 available)
Cited2tm2Bha mutation (2 available); any Cited2 mutation (23 available)
Edil3Tg(Sox2-cre)1Amc mutation (5 available); any Edil3 mutation (43 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• though present in Mendelian ratios at E15.5, mice die during late gestation or postnatal development with no mice present at weaning
• though present in Mendelian ratios at E15.5, mice die during late gestation or postnatal development with no mice present at weaning

cardiovascular system
• in some mice
• bilateral in one mouse
• some mice exhibit a common atrioventricular valve
• in some mice
• in one mouse
• in all embryos at E15.5
• abnormal ventricular topology

respiratory system
• in 6 of 10 embryos and associated with right atrial isomerism at E15.5

nervous system
• 2 mice at E15.5

endocrine/exocrine glands

growth/size/body
• in some mice
• in 6 of 10 embryos and associated with right atrial isomerism at E15.5


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory