Phenotypes for Cited2 H2az2 MGI:3804086 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Cited2^tm1Bha/Cited2^tm2Bha H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺
Genetic Background	involves: 129 * C57BL/6 * CBA * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cited2^tm1Bha mutation (3 available); any Cited2 mutation (23 available)
Cited2^tm2Bha mutation (2 available); any Cited2 mutation (23 available)
H2az2^{Tg(Wnt1-cre)11Rth} mutation (2 available); any H2az2 mutation (27 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

decreased survivor rate ( J:137951 )

• despite present in Mendelian ratios at E18.5, fewer than expected survive to weaning

postnatal lethality, incomplete penetrance ( J:137951 )

• despite present in Mendelian ratios at E18.5, fewer than expected survive to weaning

nervous system

exencephaly ( J:137951 )

• in one mouse

small geniculate ganglion ( J:137951 )

abnormal glossopharyngeal ganglion morphology ( J:137951 )

• 11 of 14 mice exhibit fusion of ganglia IX and X

small trigeminal ganglion ( J:137951 )

abnormal vagus ganglion morphology ( J:137951 )

• 11 of 14 mice exhibit fusion of ganglia IX and X

small vestibular ganglion ( J:137951 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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