Phenotypes for H2 Ptcra MGI:3807285 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	H2^b/H2^b Ptcra^tm1Vbo/Ptcra^tm1Vbo
Genetic Background	involves: 129P2/OlaHsd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H2^b mutation (28 available); any H2 mutation (282 available)
Ptcra^tm1Vbo mutation (0 available); any Ptcra mutation (16 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

decreased thymocyte number ( J:131357 )

• thymocyte number is decreased by 10-fold compared to controls

decreased double-positive T cell number ( J:131357 )

• the percentage of DP thymocytes is severely reduced in the thymocytes

spleen hypoplasia ( J:131357 )

• spleen numbers are reduced by more than 4-fold

immune system

decreased thymocyte number ( J:131357 )

• thymocyte number is decreased by 10-fold compared to controls

decreased double-positive T cell number ( J:131357 )

• the percentage of DP thymocytes is severely reduced in the thymocytes

spleen hypoplasia ( J:131357 )

• spleen numbers are reduced by more than 4-fold

endocrine/exocrine glands

decreased thymocyte number ( J:131357 )

• thymocyte number is decreased by 10-fold compared to controls

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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