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Phenotypes Associated with This Genotype
Genotype
MGI:3809246
Allelic
Composition		 Emx1tm1.1(cre)Ito/Emx1+
Tg(Gfap-GFAP*R239H)60TMIke/0
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Emx1tm1.1(cre)Ito mutation (1 available); any Emx1 mutation (34 available)
Tg(Gfap-GFAP*R239H)60TMIke mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
increased susceptibility to pharmacologically induced seizures ( J:139349 )
• frequency of severe convulsions is higher than in controls but mortality is similar to controls following with 20 mg kainate/kg

nervous system
increased susceptibility to pharmacologically induced seizures ( J:139349 )
• frequency of severe convulsions is higher than in controls but mortality is similar to controls following with 20 mg kainate/kg

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory