Phenotypes for Apobec3 H2 MGI:3809805 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Apobec3^Gt(XN450)Byg/Apobec3^Rfv3-s H2^b/H2^b
Genetic Background	involves: A.BY * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apobec3^Gt(XN450)Byg mutation (3 available); any Apobec3 mutation (125 available)
Apobec3^Rfv3-s mutation (1 available); any Apobec3 mutation (125 available)
H2^b mutation (28 available); any H2 mutation (282 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

abnormal immunoglobulin level ( J:138778 )

• the levels of neutralizing antibody produced to Friend virus 28 days after inoculation is over an order of magnitude lower than in littermate controls

hematopoietic system

abnormal immunoglobulin level ( J:138778 )

• the levels of neutralizing antibody produced to Friend virus 28 days after inoculation is over an order of magnitude lower than in littermate controls

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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