About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3810972
Allelic
Composition		 Casp7tm1Flv/Casp7tm1Flv
Genetic
Background		 B6.129S6-Casp7tm1Flv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Casp7tm1Flv mutation (1 available); any Casp7 mutation (16 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
decreased fibroblast apoptosis ( J:105496 )
• mouse embryonic fibroblasts (MEFs) exhibit a slight decrease in apoptosis rates following exposure to various insults
• following UV irradiation and staurosporine treatment, MEFs exhibit increased survival compared to wild type or Casp7tm1Flv MEFs

immune system
immune system phenotype ( J:105496 )
N
• lymphoid development and T cell apoptosis are normal

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory