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Phenotypes Associated with This Genotype
Genotype
MGI:3811102
Allelic
Composition
Abcc4Gt(RRC212)Byg/Abcc4Gt(RRC212)Byg
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Abcc4Gt(RRC212)Byg mutation (0 available); any Abcc4 mutation (153 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• following administration of capsaicin mice show an increased tolerance to weight application relative to wild-type controls
• however, baseline thresholds are similar to controls
• following administration of capsaicin mice show an prolonged latency of withdrawal from a thermal source relative to wild-type controls
• however, baseline thresholds are similar to controls

homeostasis/metabolism
• plasma levels of PGEM, a PGE1 and PGE2 metabolite, are about 50% lower than in wild-type controls


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory