Analysis Tools
hematopoietic system
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• E14.5 fetal liver cultures fail to exhibit outgrowths of erythroid progenitor cells as do wild-type livers
• mice treated with phenylhydrazine to induce anemia or exposed to hypoxic conditions fail to exhibit an increase in colony forming unit-erythroid cells unlike in similarly treated wild-type mice
• fetal liver cells transplanted into irradiated wild-type mice fail to respond normally with increased erythroid progenitor cell numbers to hypoxic conditions
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