Analysis Tools
immune system
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• T cells fail to exhibit an increase in apoptosis following treatment with dexamethasone unlike Nr3c1tm2Gsc control cells
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• following exposure to MOG, mice exhibit earlier induction of experimental autoimmune encephalomyelitis than in similarly treated wild-type mice and fail to recover after treatment with dexamethasone as do Nr3c1tm2Gsc control mice
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homeostasis/metabolism
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• T cells fail to exhibit an increase in apoptosis following treatment with dexamethasone unlike Nr3c1tm2Gsc control cells
• following induction of experimental autoimmune encephalomyelitis and treatment with dexamethasone, regulatory T cell numbers are not as diminished as in Nr3c1tm2Gsc control mice and expression of Foxp3 is unaltered
• unlike in peripheral T cells from Nr3c1tm2Gsc control mice, treatment with dexamethasone does not reduced expression of cell adhesion molecules
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cellular
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• T cells fail to exhibit an increase in apoptosis following treatment with dexamethasone unlike Nr3c1tm2Gsc control cells
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hematopoietic system
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• T cells fail to exhibit an increase in apoptosis following treatment with dexamethasone unlike Nr3c1tm2Gsc control cells
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