Phenotypes Associated with This Genotype

Genotype
MGI:3818180

• Allelic Composition: Apoe^tm1Khw/Apoe^tm1Khw; Tg(Mx1-cre)29-4Her/?
• Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

increased circulating cholesterol level ( J:75681 )

• substantial increase in plasma cholesterol on a high fat diet, reversible after cre induction with pIpC

increased circulating LDL cholesterol level ( J:75681 )

• slight on a normal diet

increased circulating VLDL cholesterol level ( J:75681 )

• slightly on a normal diet

increased circulating triglyceride level ( J:75681 )

• slight increase on a normal diet

• substantial increase on a high fat diet, reversible after cre induction using pIpC