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Phenotypes Associated with This Genotype
Genotype
MGI:3818851
Allelic
Composition		 InsrRgsc1777/Insr+
Genetic
Background		 involves: C3H * C57BL/6JJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
InsrRgsc1777 mutation (1 available); any Insr mutation (94 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
hyperglycemia ( J:133634 )
• at 54 weeks of age, the founder mouse had a serum glucose level of 537 mg/dL
• progeny of the founder have hyperglycemia and elevated HbA1c at 30 weeks
increased circulating insulin level ( J:133634 )
• progeny of the founder mouse become hyperinsulinemic

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory