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Phenotypes Associated with This Genotype
Genotype
MGI:3820424
Allelic
Composition		 Spag6ltm1Jfs/Spag6l+
Genetic
Background		 involves: 129X1/SvJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Spag6ltm1Jfs mutation (0 available); any Spag6l mutation (54 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
asthenozoospermia ( J:78433 )
• male heterozygotes were fertile but exhibited an intermadiate reduction in mean curvilinear velocity of epididymal sperm relative to homozygotes, suggesting impaired sperm swimming speed
• however, no ultrastructural flagellar abnormalities were observed

cellular
asthenozoospermia ( J:78433 )
• male heterozygotes were fertile but exhibited an intermadiate reduction in mean curvilinear velocity of epididymal sperm relative to homozygotes, suggesting impaired sperm swimming speed
• however, no ultrastructural flagellar abnormalities were observed

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory