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Phenotypes Associated with This Genotype
Genotype
MGI:3822876
Allelic
Composition		 Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
Hesx1tm1(cre)Jpmb/Hesx1tm3Jpmb
Genetic
Background		 involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1Sor mutation (7 available); any Gt(ROSA)26Sor mutation (997 available)
Hesx1tm1(cre)Jpmb mutation (0 available); any Hesx1 mutation (14 available)
Hesx1tm3Jpmb mutation (0 available); any Hesx1 mutation (14 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
decreased forebrain size ( J:142649 )
• anterior to posterior cell fate transformation is detected at 10 days post coitum, resulting in anterior forebrain reduction
• alterations are more severe than observed in corresponding Hesx1tm2Jpmb compound mutants

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/17/2024
MGI 6.24 		The Jackson Laboratory