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Phenotypes Associated with This Genotype
Genotype
MGI:3829509
Allelic
Composition
Eif3cXs/Eif3c+
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Eif3cXs mutation (2 available); any Eif3c mutation (30 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• Background Sensitivity: due to reduced penetrance or viability

limbs/digits/tail
• severe limb defects including absence of major bones
• on the hindfeet occasionally the first digit of one or both feet may be thickened, twisted, or duplicated
• develops preaxially on one or both forefeet
• the left forefoot is affected more frequently than the right

pigmentation
• not typical of all mice
• amount varies from a few white hairs to a defined patch
• usually on the belly
• not always seen

craniofacial
• occasionally the pinna is abnormal

hearing/vestibular/ear
• occasionally the pinna is abnormal

integument
• not typical of all mice
• amount varies from a few white hairs to a defined patch
• usually on the belly
• not always seen

growth/size/body
• occasionally the pinna is abnormal


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory