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Phenotypes Associated with This Genotype
Genotype
MGI:3830384
Allelic
Composition		 Zfhx3Gt(RRJ548)Byg/Zfhx3Gt(RRJ548)Byg
Genetic
Background		 involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Zfhx3Gt(RRJ548)Byg mutation (0 available); any Zfhx3 mutation (130 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
endocrine/exocrine glands
endocrine/exocrine gland phenotype ( J:143958 )
N
• despite reduced Pit1 (Pou1f1) expression, initial pituitary organ commitment, cell proliferation and early cell lineages specification are normal

homeostasis/metabolism
decreased growth hormone level ( J:143958 )
• in the pituitary at E17.5
decreased thyroid-stimulating hormone level ( J:143958 )
• in the pituitary at E17.5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory