mortality/aging
• Listeria-infected mice die by day 15 post-infection compared to Rag1tm1Mom homozygotes that die at day 4 post-infection
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immune system
• proliferation of Gr1+CD11b+ neutrophil progenitors is increased compared to in Rag1tm1Mom homozygotes
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• compared to in Rag1tm1Mom homozygotes
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• mice infected with Listeria exhibit increased neutrophil numbers and increased bacterial clearance compared to similarly treated Rag1tm1Mom homozygotes
• however, depletion of Gr-1+ neutrophils increases bacterial load in Listeria-infected mice
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• Listeria-infected mice die by day 15 post-infection compared to Rag1tm1Mom homozygotes that die at day 4 post-infection
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hematopoietic system
• proliferation of Gr1+CD11b+ neutrophil progenitors is increased compared to in Rag1tm1Mom homozygotes
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• compared to in Rag1tm1Mom homozygotes
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cellular
• proliferation of Gr1+CD11b+ neutrophil progenitors is increased compared to in Rag1tm1Mom homozygotes
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growth/size/body