Analysis Tools
mortality/aging
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• 60% mortality at day 12 after inoculation with C. rodentium
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immune system
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• mice challenged with Staphylococcus epidermidis cell-free supernatant exhibit impaired T cells (including CD4+, Th1, and Th17 cells) recruitment and production of IL17a compared with similarly treated wild-type mice
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• mice challenged with Staphylococcus epidermidis cell-free supernatant exhibit fewer IL17a producing cells compared to in similarly treated wild-type mice
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• following carrageenan induced inflammation, mice exhibit impaired neutrophil resolution after 7 days and delayed macrophage infiltration compared to in similarly treated wild-type mice
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• 60% mortality at day 12 after inoculation with C. rodentium
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homeostasis/metabolism
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• at healing wounds, mice exhibit delayed re-epithelialization, formation of granulation tissue, macrophage infiltration, fibrin clearance, and vascularization compared with wild-type mice
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• wounds become expanded beyond the boundaries of the original wound unlike in wild-type mice
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• 24 hours after scalpel cortex injury, mice exhibit reduced microglial and astrocyte reaction compared with similarly treated wild-type mice
(J:89814)
• following exposure to acid-induced acute lung injury, mice exhibit alleviated symptoms compared to wild-type mice
(J:145306)
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liver/biliary system
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• modestly reduced oval cell response to a choline deficient diet and ethionine in the drinking water
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nervous system
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• 24 hours after scalpel cortex injury, mice exhibit reduced microglial and astrocyte reaction compared with similarly treated wild-type mice
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hematopoietic system
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• mice challenged with Staphylococcus epidermidis cell-free supernatant exhibit impaired T cells (including CD4+, Th1, and Th17 cells) recruitment and production of IL17a compared with similarly treated wild-type mice
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