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Phenotypes Associated with This Genotype
Genotype
MGI:3837663
Allelic
Composition		 Il6sttm1Ern/Il6st+
Smad3tm1Par/Smad3+
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il6sttm1Ern mutation (13 available); any Il6st mutation (80 available)
Smad3tm1Par mutation (2 available); any Smad3 mutation (23 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased adenoma incidence ( J:100160 )
• develop antral adenomas by 13-24 weeks of age

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory