Phenotypes for Ptpn11 Tg(Tek-cre)12Flv MGI:3840254 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Ptpn11^tm6Bgn/Ptpn11⁺ Tg(Tek-cre)12Flv/0
Genetic Background	involves: 129S6/SvEvTac * C3H * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptpn11^tm6Bgn mutation (2 available); any Ptpn11 mutation (46 available)
Tg(Tek-cre)12Flv mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality ( J:147154 )

cardiovascular system

thin myocardium ( J:147154 )

• seen at E13.5

increased atrioventricular cushion size ( J:147154 )

• seen at E11.5 and E13.5

double outlet right ventricle ( J:147154 )

ventricular septal defect ( J:147154 )

muscle

thin myocardium ( J:147154 )

• seen at E13.5

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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