mortality/aging
• severely affected mice die around weaning
|
skeleton
fused joints
(
J:77537
)
• elbow joints and eventually knee joints fuse unlike in wild-type mice
|
synostosis
(
J:146802
)
• in the cartilaginous components of the elbow joint
|
growth/size/body
• mice exhibit growth retardation compared to wild-type mice
• however, mice eventually catch up to wild-type mice
|
limbs/digits/tail
kinked tail
(
J:77537
)