Phenotypes for Scn8a MGI:3840662 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Scn8a^nur14/Scn8a^nur14
Genetic Background	C57BL/6J-Scn8a^nur14

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scn8a^nur14 mutation (0 available); any Scn8a mutation (99 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

premature death ( J:146758 )

• mice do not survive beyond 1 month of age

behavior/neurological

tremors ( J:146758 )

• pronounced

ataxia ( J:146758 )

• ataxic gait

hindlimb paralysis ( J:146758 )

• mice exhibit partial loss of hindlimb function by 2 weeks of age

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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