Phenotypes Associated with This Genotype

Genotype
MGI:3841064

• Allelic Composition: Atxn1^tm2Zuk/Atxn1^tm2Zuk
• Genetic Background: either: (involves: 129S/SvEv) or (involves: 129S7/SvEvBrd * C57BL/6)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

impaired coordination ( J:61398 )

• rotarod performance deteriorates with age

• normal at 3 months, slightly deficient at 6 months, and significantly poor a 9 months

• Background Sensitivity: performance is somewhat better on a "pure" 129/SvEv background

• no ataxia or other gross abnormalities up to 18 months of age