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Phenotypes Associated with This Genotype
Genotype
MGI:3846351
Allelic
Composition		 Gli2tm2.1Alj/Gli2+
Shhtm1Chg/Shhtm1Chg
Genetic
Background		 either: (involves: 129) or (involves: 129 * Black Swiss)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gli2tm2.1Alj mutation (1 available); any Gli2 mutation (169 available)
Shhtm1Chg mutation (2 available); any Shh mutation (48 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo

nervous system
abnormal telencephalon development ( J:73074 )
• fused telencephalic vesicles are seen at E10.5
abnormal spinal cord morphology ( J:73074 )
• loss of many ventral tissues is seen at E10.5

growth/size/body
decreased embryo size ( J:73074 )
• at E10.5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory