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Phenotypes Associated with This Genotype
Genotype
MGI:3848618
Allelic
Composition
Mogat2tm1Far/Mogat2tm1Far
Genetic
Background
B6.129S4-Mogat2tm1Far
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mogat2tm1Far mutation (1 available); any Mogat2 mutation (21 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• when fed an increased amount of fat, less lipids enter circulation compared to wild-type mice
• at 16 weeks on a high fat diet, mice weigh 40% less than in similarly treated wild-type mice
• female mice fed a 60% high fat diet and male mice fed a 45% high fat diet exhibit decreased weight gain compared to similarly treated wild-type mice
• mice fed a high fat diet exhibit lower fasting insulin serum levels than in similarly treated wild-type mice
• when fed a high fat diet
• when fed a high fat diet, non-HDL serum cholesterol levels are lower than in similarly treated wild-type mice
• when fed a high fat diet, non-HDL serum cholesterol levels are lower than in similarly treated wild-type mice
• following intragastric bolus of olive oil
• when fed a high fat diet
• increased 7% when fed a high fat diet
• when fed a high fat diet
• when fed a high fat diet

adipose tissue
• when fed a high fat diet
• at 16 weeks on a high fat diet, fat mass is more than 50% lower than in similarly treated wild-type mice

growth/size/body
• at 16 weeks on a high fat diet, mice weigh 40% less than in similarly treated wild-type mice
• female mice fed a 60% high fat diet and male mice fed a 45% high fat diet exhibit decreased weight gain compared to similarly treated wild-type mice

liver/biliary system

digestive/alimentary system
• when fed an increased amount of fat, less lipids enter circulation compared to wild-type mice


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory