Phenotypes for Gt(ROSA)26Sor Shh Tg(Prrx1-cre)1Cjt MGI:3848911 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Gt(ROSA)26Sor^{tm5(Etv4/en,-GFP)Amc}/Gt(ROSA)26Sor⁺ Shh^tm1Amc/Shh^tm2Amc Tg(Prrx1-cre)1Cjt/0
Genetic Background	involves: 129 * C57BL/6 * CBA * SJL/J * Swiss Webster

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sor^{tm5(Etv4/en,-GFP)Amc} mutation (0 available); any Gt(ROSA)26Sor mutation (1024 available)
Shh^tm1Amc mutation (1 available); any Shh mutation (48 available)
Shh^tm2Amc mutation (1 available); any Shh mutation (48 available)
Tg(Prrx1-cre)1Cjt mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

abnormal digit morphology ( J:149478 )

• at P1, digits appear posteriorized comparing relative digit length and phalanx morphology with that of controls Shh^tm1Amc/Shh^tm2Amc Tg(Prrx1-cre)1Cjt mice

• however, mice have the same number of digits as in Shh^tm1Amc/Shh^tm2Amc Tg(Prrx1-cre)1Cjt mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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