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Phenotypes Associated with This Genotype
Genotype
MGI:3849290
Allelic
Composition		 Rag2tm1Fwa/Rag2tm1Fwa
Rr299391tm1.1Fwa/Rr299391tm1.1Fwa
Genetic
Background		 involves: 129P2/OlaHsd * 129S/SvEv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rag2tm1Fwa mutation (48 available); any Rag2 mutation (117 available)
Rr299391tm1.1Fwa mutation (0 available); any Rr299391 mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal T cell receptor delta chain V(D)J recombination ( J:149413 )
• transcript analysis of double-negative thymocytes reveals a 10-fold drop in use of the Tcrd-V5 gene segment

hematopoietic system
abnormal T cell receptor delta chain V(D)J recombination ( J:149413 )
• transcript analysis of double-negative thymocytes reveals a 10-fold drop in use of the Tcrd-V5 gene segment

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory