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Phenotypes Associated with This Genotype
Genotype
MGI:3850242
Allelic
Composition		 Rgs11tm1Lex/Rgs11tm1Lex
Rgs7tm1Lex/Rgs7tm1Lex
Genetic
Background		 involves: 129S5/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rgs11tm1Lex mutation (2 available); any Rgs11 mutation (31 available)
Rgs7tm1Lex mutation (2 available); any Rgs7 mutation (26 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
abnormal eye electrophysiology ( J:150122 )
• mice exhibit additive effects on time course of the dark-adapted electroretinogram responses arising from bipolar cells
abnormal rod electrophysiology ( J:150122 )
• negative-scotopic threshold response is reduced compared to in wild-type mice or single mutants

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory