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Phenotypes Associated with This Genotype
Genotype
MGI:3850405
Allelic
Composition
Nf2tm2Gth/Nf2+
Tg(Mpz-cre)#Brn/0
Genetic
Background
involves: 129P2/OlaHsd * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nf2tm2Gth mutation (3 available); any Nf2 mutation (65 available)
Tg(Mpz-cre)#Brn mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands
• 6% of mice exhibit fibroadenoma in the mammary gland

neoplasm
• 6% of mice exhibit fibroadenoma in the mammary gland
• 6% of mice develop osteoma

integument
• 6% of mice exhibit fibroadenoma in the mammary gland

nervous system
N
• mice exhibit normal Schwann cell proliferation

respiratory system

craniofacial
• 6% of mice exhibit odontoblastic hyperplasia

skeleton
• 6% of mice exhibit odontoblastic hyperplasia
• 6% of mice develop osteoma

growth/size/body
• 6% of mice exhibit odontoblastic hyperplasia


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/17/2024
MGI 6.24
The Jackson Laboratory