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Phenotypes Associated with This Genotype
Genotype
MGI:3851392
Allelic
Composition		 Mthfrtm1Rzn/Mthfrtm1Rzn
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * BALB/cAnNCrl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mthfrtm1Rzn mutation (2 available); any Mthfr mutation (70 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
homeostasis/metabolism phenotype ( J:150548 )
N
• N-homocysteine levels are normal in the liver and heart and total homocysteine levels are normal in the liver
increased circulating homocysteine level ( J:150548 )
• plasma N-homocysteine levels are higher than in heterozygous or wild-type mice
• total plasma homocysteine level is mildly elevated compared to in heterozygous and wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory