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Phenotypes Associated with This Genotype
Genotype
MGI:4353052
Allelic
Composition		 Nqo1tm1Msho/Nqo1tm1Msho
Genetic
Background		 involves: 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nqo1tm1Msho mutation (0 available); any Nqo1 mutation (26 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal cell physiology ( J:151045 )
• absence of beta-lapachone induced phosphorylations of AMP activated protein kinase and acetyl-CoA carboxylase in MEFs, unlike in heterozygous MEFs

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory