Phenotypes for Rb1 Rbl1 MGI:4353990 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Rb1^tm1Tyj/Rb1^tm1Tyj Rbl1^tm1Mru/Rbl1^tm1Mru
Genetic Background	involves: 129S2/SvPas * 129S4/SvJae * BALB/c * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rb1^tm1Tyj mutation (5 available); any Rb1 mutation (111 available)
Rbl1^tm1Mru mutation (0 available); any Rbl1 mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

increased neuronal precursor cell number ( J:92520 )

• mice exhibit increased neuronal precursor numbers due to increased proliferation

• cultured E10 telencephalic neuroepithelia produces more primary neurospheres than cultures from wild-type mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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