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Phenotypes Associated with This Genotype
Genotype
MGI:4355068
Allelic
Composition		 Lhx1tm1Bhr/Lhx1tm1Bhr
Pgap1oto/Pgap1+
Genetic
Background		 involves: 129S7/SvEvBrd * C57BL/6J * STOCK In(1)1Rk/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lhx1tm1Bhr mutation (2 available); any Lhx1 mutation (22 available)
Pgap1oto mutation (0 available); any Pgap1 mutation (53 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
abnormal developmental patterning ( J:41878 )
• some mice lack a well-developed body axis

nervous system
abnormal brain morphology ( J:41878 )
• at E9 to E9.5, anterior truncations are more severe than in Lhx1tm1Bhr homozygotes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/17/2024
MGI 6.24 		The Jackson Laboratory