Phenotypes Associated with This Genotype

Genotype
MGI:4398699

• Allelic Composition: Epha4^tm2Kldr/Epha4^tm2Kldr; Tg(Pgk1-cre)1Lni/0
• Genetic Background: involves: BALB/c * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal anterior commissure morphology ( J:154648 )

• the anterior commissure does not form in its normal location

abnormal spinal cord dorsal column morphology ( J:154648 )

• the ventral part of the dorsal funiculus is reduced and the distance between the dorsal funiculus and the central canal is increased compared to in Epha4^tm2Kldr control mice

behavior/neurological

abnormal gait ( J:154648 )

• mice exhibit a hopping gait unlike Epha4^tm2Kldr control mice