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Phenotypes Associated with This Genotype
Genotype
MGI:4417858
Allelic
Composition		 Gata3tm1Iho/Gata3tm1Iho
Tg(Cd4-cre)1Cwi/0
Tg(DO11.10)10Dlo/0
Genetic
Background		 involves: BALB/c * C3H * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gata3tm1Iho mutation (0 available); any Gata3 mutation (32 available)
Tg(Cd4-cre)1Cwi mutation (10 available)
Tg(DO11.10)10Dlo mutation (7 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased CD4-positive, alpha-beta T cell number ( J:86996 )
• severe reduction in single positive (SP) CD4 cells and no enrichment of SP CD8 cells

immune system
decreased CD4-positive, alpha-beta T cell number ( J:86996 )
• severe reduction in single positive (SP) CD4 cells and no enrichment of SP CD8 cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory