Analysis Tools
mortality/aging
|
• 1 week after birth, mice are dead
|
nervous system
|
• mice exhibit impaired development of retrotapezoid nucleus neurons compared with wild-type mice
|
|
• the parafacial area e-pF oscillator exhibits only occasional motor activity bursts with reduced frequency compared to in wild-type mice
• rhythmic phrenic discharges are less frequent than in wild-type mice
• mice fail to exhibit an accelerated respiratory-like rhythm phrenic discharge in response to low pH challenge unlike similarly treated wild-type mice
|
cellular
|
• mice exhibit impaired development of retrotapezoid nucleus neurons compared with wild-type mice
|
