Phenotypes Associated with This Genotype

Genotype
MGI:4437875

• Allelic Composition: Rdh10^m366Asp/Rdh10^m366Asp
• Genetic Background: involves: C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

nervous system phenotype ( J:157301 )

N • mice exhibit normal meninges

abnormal forebrain morphology ( J:157301 )

• at E13.5, the dorsal forebrain is longer and thinner Tuj1+ layer than in wild-type mice

abnormal cerebral cortex morphology ( J:157301 )

• thinner than normal at E16.5

vision/eye

abnormal eye morphology ( J:157301 )

• mice exhibit similar defects as observed in Rdh10^trex homozygotes

craniofacial

abnormal craniofacial morphology ( J:157301 )

• mice exhibit similar defects as observed in Rdh10^trex homozygotes

limbs/digits/tail

abnormal limb morphology ( J:157301 )

• mice exhibit similar defects as observed in Rdh10^trex homozygotes